The website addresses listed below link to New York State and US Environmental Protection Agency technical documents that guide the testing activities within Aquatox Research.
NYS DEC. 2007. Division of Water Technical and Operational Guidance Series (TOGS), 1.3.2., Acute and Chronic Toxicity Testing in the SPDES Program Guidance
appearing at: http://www.dec.ny.gov/docs/water_pdf/togs132.pdf
U.S. Environmental Protection Agency. 2002. Methods for Measuring the Acute Toxicity of Effluents and Receiving Waters to Freshwater and Marine Organisms. 5th Ed. EPA-821-R-02-012. Office of Water (4303T), 1200 Pennsylvania Avenue, Washington DC 20460
appearing at: https://www.wbdg.org/FFC/EPA/EPACRIT/epa821_r_02_012.pdf
U.S. Environmental Protection Agency. 2002. Short-Term Methods for Estimating the Chronic Toxicity of Effluents and Receiving Waters to Freshwater Organisms. 4th Ed. EPA-821-R-02-013. Office of Water, Washington DC.
appearing at: https://www.epa.gov/sites/production/files/2015-08/documents/short-term-chronic-freshwater-wet-manual_2002.pdf